If you are taking cyclosporine neoral, sandimmune , take it 2 hours before or 2 hours after orlistat.
FDAFDA Drug Safety CommunicationCompleted Safety Review of Xenical/Alliorlistatand Severe Liver InjuryandMedications Target Long-Term Weight Control
Rememberkeep this and all other medicines out of the reach of childrennever share your medicines with othersand use orlistat only for the indication prescribed.
For patients receiving both XENICAL and levothyroxine therapyadminister levothyroxine and XENICAL at least 4 hours apartPatients treated concomitantly with XENICAL and levothyroxine should be monitored for changes in thyroid function.
Some side effects can be seriousIf you experience any of these symptomscall your doctor immediately:
Patients should be informed of the commonly-observed adverse events associated with the use of XENICAL which include oily spottingflatus with dischargefecal urgencyfatty/oily stooloily evacuationincreased defecationfecal incontinencesee ADVERSE REACTIONS
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